About Maastricht University
The University of Maastricht (UNIMA) is situated in the southern part of the Netherlands, close to the borders of both Belgium and Germany. It has approximately 3.500 staff members and 14.500 students. The Academic Hospital Maastricht and Maastricht University work together under the heading of Maastricht University Medical center (MUMC). The latter however is not a legal entity in itself; only the Academic Hospital and Maastricht University are legal entities. The Maastricht University as part of the MUMC will take the responsibility of delivering the reports for the project.
The department of General Surgery performs two main tasks: delivering medical care at the highest standards and performing research in surgical topics. The research part of this department has several main areas of interest, of which improving gastrointestinal anastomosis is one. The department has extensive collaborations with neighboring universities such as Aachen (Germany) and Leuven (Belgium).
Relevant experience in relation to the project
Bloemen JG, Schreinemacher MH, de Bruine AP, Buurman WA, Bouvy ND, Dejong CH. Butyrate enemas improve intestinal anastomotic strength in a rat model. Dis Colon Rectum. 2010 Jul;53(7):1069-75.
– Schreinemacher MH, Bloemen JG, van der Heijden SJ, Gijbels MJ, Dejong CH, Bouvy ND. Collagen fleeces do not improve colonic anastomotic strength but increase bowel obstructions in an experimental rat model. Int J Colorectal Dis. 2011.
– Schreinemacher MH, Vijgen GH, Dagnelie PC, Bloemen JG, Huizinga BF, Bouvy ND. Incisional hernias in temporary stoma wounds: a cohort study. Arch Surg. 2011 Jan;146(1):94-9.
– Schreinemacher MH, ten Broek RP, Bakkum EA, van Goor H, Bouvy ND. Adhesion awareness: a national survey of surgeons. World J Surg. 2010 Dec;34(12):2805-12.
– Schreinemacher M, Henatsch D, van Barneveld K, Bouvy N. The need for standardised animal models and scoring systems in assessing mesh biocompatibility. Hernia. 2010 Jun;14(3):335-6.
– Schreinemacher MH, Emans PJ, Gijbels MJ, Greve JW, Beets GL, Bouvy ND. Degradation of mesh coatings and intraperitoneal adhesion formation in an experimental model. Br J Surg. 2009 Mar;96(3):305-13.
– Emans PJ, Schreinemacher MH, Gijbels MJ, Beets GL, Greve JW, Koole LH, Bouvy ND. Polypropylene meshes to prevent abdominal herniation. Can stable coatings prevent adhesions in the long term? Ann Biomed Eng. 2009 Feb;37(2):410-8
Contributions to the AnastomoSEAL Project
UNIMA will contribute in the AnastomoSEAL project performing the following tasks:
- to test the different patches in vitro, together with UNITS
- to develop and coordinate two animal models to test the patches in vivo,
- to perform all animal experiments,
- to analyse tissues derived from these animal experiments ex vivo
- to disseminate the knowledge and results at scientific congresses and in scientific papers.
Maastricht University Staff Members involved in AnastomoSEAL
Prof. Dr. Nicole D. Bouvy, MD, PhD, Surgeon, Associate professor of surgery, is one of the staff members of the department of General Surgery of the Maastricht University Medical Centre (MUMC). She is the co-promotor of several PhD-students and has extensive experience in both clinical and experimental surgical research.
Drs. Anne-Claire Bosmans, MD, is currently a PhD-candidate at the MUMC+. Her main subject is anastomotic leakage after colorectal surgery; risk factors, effects of adhesion prevention on anastomotic healing and potential prevention of anastomotic leakage.
Former Staff Members involved in the project
Drs. Kevin W.Y. van Barneveld, MD, PhD-student, surgical resident, is currently PhD-student at the MUMC. His research topics are abdominal related: abdmoninal hernia, surgical meshes, intraabdominal adhesions and gastrointestinal anastomosis.
Drs. Marc H.F. Schreinemacher, MD, PhD-student, surgical resident, is currently finishing his PhD at the MUMC. His research topics are also abdominal related: incisional hernia, surgical meshes, intraabdominal adhesions and colonic anastomosis.